Tissue disruption increases stochastic gene expression thus producing tumors: Cancer initiation without driver mutation
نویسندگان
چکیده
منابع مشابه
Evaluation of BRAF-V600E gene mutation in colon tissue of patients with colorectal cancer in Iran
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متن کاملGene disruption of tissue transglutaminase.
Transglutaminase 2 (TGase 2), or tissue transglutaminase, catalyzes either epsilon-(gamma-glutamyl)lysine or N(1), N(8)-(gamma-glutamyl)spermidine isopeptide bonds. TGase 2 expression has been associated with apoptosis, and it has been proposed that its activation should lead to the irreversible assembly of a cross-linked protein scaffold in dead cells. Thus, TGase 2-catalyzed protein polymeriz...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2017
ISSN: 0020-7136
DOI: 10.1002/ijc.30596